Ajit, S. (Singh)

What are ‘Antibodies’? ; B lymphocyte clones differentiate into plasma cells that secrete Abs ; Abs are heterogeneous glycoproteins that share many common physico-chemical and ; structural features ; Shapes of antigen-binding site/ paratope ; Dissecting the structure of Abs in order to understand their functions ; Antibodies vis-a-vis enzymes ; Different Ab classes and subclasses are for diverse effector functions ; Structural variants of Abs are genetically determined and antigenically distinguishable ; Biological functions of Abs ; Abs as biocatalysts ; Forces involved in antibody-antigen interactions ; Affinity, avidity and specificity of antibodies ; Ig genes and generation of antibody diversity ; Major genetic mechanisms that diversify Ab specificities and effector functions ; Theories of antibody production - A brief account ; Immunotechnology for production of antibodies and the ‘antigen-binder’ fragments ; Origin and Evolution of Igs ; Immunoglobulin superfamily (IgSF) ;

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National Institute of Science Communication and Information Resources (NISCAIR)

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